Lepisto A | Seppälä Labhttps://www.seppalalab.org/author/lepisto-a/Lepisto AHugo Blox Builder (https://hugoblox.com)enThu, 01 Jan 2026 00:00:00 +0000https://www.seppalalab.org/media/logo_hu_e3f0d28ad302f75b.pngLepisto Ahttps://www.seppalalab.org/author/lepisto-a/Nanopore sequencing reveals hidden landscape of short L1 transductions in colorectal cancerhttps://www.seppalalab.org/publication/nummi-2026-nanopore/Thu, 01 Jan 2026 00:00:00 +0000https://www.seppalalab.org/publication/nummi-2026-nanopore/Tumour immune contexture and immune evasion in sporadic and Lynch syndrome-associated microsatellite unstable colorectal cancershttps://www.seppalalab.org/publication/martin-2026-tumour/Thu, 01 Jan 2026 00:00:00 +0000https://www.seppalalab.org/publication/martin-2026-tumour/Comprehensive metabolomic and epigenomic characterization of microsatellite stable BRAF-mutated colorectal cancerhttps://www.seppalalab.org/publication/taira-2025-comprehensive/Wed, 01 Jan 2025 00:00:00 +0000https://www.seppalalab.org/publication/taira-2025-comprehensive/Genome-wide DNA methylation profiles of colorectal tumors in Lynch syndrome and familial adenomatous polyposishttps://www.seppalalab.org/publication/maki-nevala-2025-genome-wide/Wed, 01 Jan 2025 00:00:00 +0000https://www.seppalalab.org/publication/maki-nevala-2025-genome-wide/Performance Comparison of Droplet Digital PCR and Next-Generation Sequencing for Circulating Tumor DNA Detection in Non-Metastatic Rectal Cancerhttps://www.seppalalab.org/publication/szeto-2025-performance/Wed, 01 Jan 2025 00:00:00 +0000https://www.seppalalab.org/publication/szeto-2025-performance/Structural features of somatic and germline retrotransposition events in humanshttps://www.seppalalab.org/publication/nummi-2025-structural/Wed, 01 Jan 2025 00:00:00 +0000https://www.seppalalab.org/publication/nummi-2025-structural/Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome databasehttps://www.seppalalab.org/publication/dominguez-valentin-2023-mortality/Sun, 01 Jan 2023 00:00:00 +0000https://www.seppalalab.org/publication/dominguez-valentin-2023-mortality/Systemic circulating microRNA landscape in Lynch syndromehttps://www.seppalalab.org/publication/sievanen-2023-systemic/Sun, 01 Jan 2023 00:00:00 +0000https://www.seppalalab.org/publication/sievanen-2023-systemic/Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivityhttps://www.seppalalab.org/publication/kansikas-2023-tumor-independent/Sun, 01 Jan 2023 00:00:00 +0000https://www.seppalalab.org/publication/kansikas-2023-tumor-independent/Distinct Mutational Profile of Lynch Syndrome Colorectal Cancers Diagnosed under Regular Colonoscopy Surveillancehttps://www.seppalalab.org/publication/ahadova-2021-distinct/Fri, 01 Jan 2021 00:00:00 +0000https://www.seppalalab.org/publication/ahadova-2021-distinct/Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease-Associated Colorectal Cancerhttps://www.seppalalab.org/publication/rajamaki-2021-genetic/Fri, 01 Jan 2021 00:00:00 +0000https://www.seppalalab.org/publication/rajamaki-2021-genetic/Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesishttps://www.seppalalab.org/publication/maki-nevala-2021-immunoprofiles/Fri, 01 Jan 2021 00:00:00 +0000https://www.seppalalab.org/publication/maki-nevala-2021-immunoprofiles/No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Studyhttps://www.seppalalab.org/publication/dominguez-valentin-2021-no/Fri, 01 Jan 2021 00:00:00 +0000https://www.seppalalab.org/publication/dominguez-valentin-2021-no/Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database reporthttps://www.seppalalab.org/publication/dominguez-valentin-2021-risk-reducing/Fri, 01 Jan 2021 00:00:00 +0000https://www.seppalalab.org/publication/dominguez-valentin-2021-risk-reducing/Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database reporthttps://www.seppalalab.org/publication/seppala-2021-uptake/Fri, 01 Jan 2021 00:00:00 +0000https://www.seppalalab.org/publication/seppala-2021-uptake/Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndromehttps://www.seppalalab.org/publication/engel-2020-associations/Wed, 01 Jan 2020 00:00:00 +0000https://www.seppalalab.org/publication/engel-2020-associations/Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancershttps://www.seppalalab.org/publication/hanninen-2019-exome/Tue, 01 Jan 2019 00:00:00 +0000https://www.seppalalab.org/publication/hanninen-2019-exome/Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database reporthttps://www.seppalalab.org/publication/seppala-2019-lack/Tue, 01 Jan 2019 00:00:00 +0000https://www.seppalalab.org/publication/seppala-2019-lack/Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database reporthttps://www.seppalalab.org/publication/dominguez-valentin-2019-survival/Tue, 01 Jan 2019 00:00:00 +0000https://www.seppalalab.org/publication/dominguez-valentin-2019-survival/